In vitro activity of TD-6424 against Staphylococcus aureus.

نویسندگان

  • John L Pace
  • Kevin Krause
  • Deborah Johnston
  • Dmitri Debabov
  • Terry Wu
  • Lesley Farrington
  • Cassie Lane
  • Deborah L Higgins
  • Burt Christensen
  • J Kevin Judice
  • Koné Kaniga
چکیده

TD-6424, a rapidly bactericidal agent with multiple mechanisms of action, is more potent in vitro and more rapidly bactericidal than currently available agents against methicillin-susceptible and methicillin-resistant Staphylococcus aureus. TD-6424 produces a postantibiotic effect with a duration of 4 to 6 h against these organisms. The results suggest potential efficacy against susceptible and resistant strains of S. aureus.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 47 11  شماره 

صفحات  -

تاریخ انتشار 2003